Drugs of abuse encompass a wide range of substances that pose significant health and legal risks due to their potential for addiction and harmful effects. Toxicology screening is a critical tool used to detect these substances in biological samples, aiding in medical, forensic, and workplace contexts. Commonly misused drugs include stimulants, depressants, hallucinogens, and opioids, each with distinct physiological impacts. Screening identifies recent use, guiding treatment or legal actions. Advanced methods, like those employed by Poly Labs, enhance detection accuracy, ensuring reliable results. Such screenings are vital for addressing substance abuse, promoting public safety, and supporting rehabilitation efforts.